Morphological indices as a risk factor for rupture of intracanial aneurysms

Solapas principales

Vidaurreta J.1, Lujan J.1, Oland D.1, Toco I.1, Gamiño I. 2, Ugarte M.2, Jiménez T.3, Zarate A.1



            The annual incidence of aneurysmal rupture ranges from 6 to 21.6 cases per 100,000 inhabitants, with a risk of 1.3% per year, increasing this risk up to 6% in aneurysms bigger than 25 mm1-7. We will focus on those morphological risk factors, assessing various measurements and index to determine if there is a direct relationship between morphology and risk of rupture. We evaluated patients with a diagnosis of intracranial aneurysm at a hospital in Mexico City from January 1, 2013 to June 30, 2015. We included 103 patients with 131 intracranial aneurysms (ruptured, non-ruptured and incidental) , Who had angiotomography; We performed measurements (maximum height, maximum diameter, neck diameter, orthogonal diameter and diameter of the parent vessel) and calculated the indices (Aspect ratio, Bottleneck factor, Size ratio and Size ratio 2). The most frequent location was the posterior communicating segment; We compared the measurements of aneurysms between the ruptured and non-ruptured group, obtaining results with no statistical significance when predicting the risk of rupture. However, when evaluating morphological index, we can predict a statistically significant risk (p <0.00001) Morphometric Height-Widht Ratio is the one with the highest significance (p <0.00004).

Key Words: Morphological index, intracranial aneurysm, measurement, rupture risk.


  1. Centro Médico Nacional “20 de Noviembre”, Ciudad de México.
  2. Hospital Central Cruz Roja Mexicana, Ciudad de México.
  3. Facultad de Medicina, Universidad Anáhuac, Ciudad de México.